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	Provedor de dados BJMBR (5) Autor Leite-Panissi,C.R.A. (5) Branco,L.G.S. (2) Brentegani,M.R. (2) Carvalho-Costa,P.G. (2) Menescal-de-Oliveira,L. (2) Gerlach,R.F. (1) Nascimento,G.C. (1) Rizzi,E. (1) Rodrigues,C.L. (1) Mais... Palavra-chave Antinociception (3) Naloxone (2) Acute stress (1) Amygdala (1) Analgesia (1) Atropine (1) CGMP (1) Carbon monoxide (1) Cholinergic-opioidergic interaction (1) Guinea pig (1) Heme oxygenase (1) Heme oxygenase Carbon monoxide Locus coeruleus Anxiety Elevated plus maze (1) Lateral cerebral ventricle (1) Light/dark box (1) Matrix metalloproteinases (1) Opioids (1) Persistent temporomandibular inflammation (1) Tonic immobility (1) Trigeminal ganglion (1) Vocalization test (1) Mais... Tipo do documento Info:eu-repo/semantics/article (5) Ano 2016 (1) 2014 (1) 2013 (1) 2004 (1) 2001 (1) País Brazil (5) Idioma Inglês (5)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 5 Primeira ... 1 ... Última Activation of locus coeruleus heme oxygenase-carbon monoxide pathway promoted an anxiolytic-like effect in rats BJMBR Carvalho-Costa,P.G.; Branco,L.G.S.; Leite-Panissi,C.R.A.. The heme oxygenase-carbon monoxide pathway has been shown to play an important role in many physiological processes and is capable of altering nociception modulation in the nervous system by stimulating soluble guanylate cyclase (sGC). In the central nervous system, the locus coeruleus (LC) is known to be a region that expresses the heme oxygenase enzyme (HO), which catalyzes the metabolism of heme to carbon monoxide (CO). Additionally, several lines of evidence have suggested that the LC can be involved in the modulation of emotional states such as fear and anxiety. The purpose of this investigation was to evaluate the activation of the heme oxygenase-carbon monoxide pathway in the LC in the modulation of anxiety by using the elevated plus maze test (EPM)... Tipo: Info:eu-repo/semantics/article Palavras-chave: Heme oxygenase Carbon monoxide Locus coeruleus Anxiety Elevated plus maze; Light/dark box. Ano: 2016 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2016000500601 Acute stress-induced antinociception is cGMP-dependent but heme oxygenase-independent BJMBR Carvalho-Costa,P.G.; Branco,L.G.S.; Leite-Panissi,C.R.A.. Endogenous carbon monoxide (CO), which is produced by the enzyme heme oxygenase (HO), participates as a neuromodulator in physiological processes such as thermoregulation and nociception by stimulating the formation of 3′,5′-cyclic guanosine monophosphate (cGMP). In particular, the acute physical restraint-induced fever of rats can be blocked by inhibiting the enzyme HO. A previous study reported that the HO-CO-cGMP pathway plays a key phasic antinociceptive role in modulating noninflammatory acute pain. Thus, this study evaluated the involvement of the HO-CO-cGMP pathway in antinociception induced by acute stress in male Wistar rats (250-300 g; n=8/group) using the analgesia index (AI) in the tail flick test. The results showed that antinociception... Tipo: Info:eu-repo/semantics/article Palavras-chave: Heme oxygenase; Carbon monoxide; CGMP; Lateral cerebral ventricle; Acute stress; Antinociception. Ano: 2014 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2014001201057 Cholinergic-opioidergic interaction in the central amygdala induces antinociception in the guinea pig BJMBR Leite-Panissi,C.R.A.; Brentegani,M.R.; Menescal-de-Oliveira,L.. Several studies have demonstrated the involvement of the central nucleus of the amygdala (CEA) in the modulation of defensive behavior and in antinociceptive regulation. In a previous study, we demonstrated the existence of a cholinergic-opioidergic interaction in the CEA, modulating the defensive response of tonic immobility in guinea pigs. In the present study, we investigated a similar interaction in the CEA, but now involved in the regulation of the nociceptive response. Microinjection of carbachol (2.7 nmol) and morphine (2.2 nmol) into the CEA promoted antinociception up to 45 min after microinjection in guinea pigs as determined by a decrease in the vocalization index in the vocalization test. This test consists of the application of a peripheral... Tipo: Info:eu-repo/semantics/article Palavras-chave: Antinociception; Vocalization test; Cholinergic-opioidergic interaction; Amygdala; Naloxone; Atropine. Ano: 2004 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2004001000018 Endogenous opiate analgesia induced by tonic immobility in guinea pigs BJMBR Leite-Panissi,C.R.A.; Rodrigues,C.L.; Brentegani,M.R.; Menescal-de-Oliveira,L.. A function of the endogenous analgesic system is to prevent recuperative behaviors generated by tissue damage, thus preventing the emission of species-specific defensive behaviors. Activation of intrinsic nociception is fundamental for the maintenance of the behavioral strategy adopted. Tonic immobility (TI) is an inborn defensive behavior characterized by a temporary state of profound and reversible motor inhibition elicited by some forms of physical restraint. We studied the effect of TI behavior on nociception produced by the formalin and hot-plate tests in guinea pigs. The induction of TI produced a significant decrease in the number of flinches (18 ± 6 and 2 ± 1 in phases 1 and 2) and lickings (6 ± 2 and 1 ± 1 in phases 1 and 2) in the formalin test... Tipo: Info:eu-repo/semantics/article Palavras-chave: Tonic immobility; Guinea pig; Antinociception; Opioids; Naloxone; Analgesia. Ano: 2001 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2001000200013 Expression of MMP-2 and MMP-9 in the rat trigeminal ganglion during the development of temporomandibular joint inflammation BJMBR Nascimento,G.C.; Rizzi,E.; Gerlach,R.F.; Leite-Panissi,C.R.A.. Orofacial pain is a prevalent symptom in modern society. Some musculoskeletal orofacial pain is caused by temporomandibular disorders (TMDs). This condition has a multi-factorial etiology, including emotional factors and alteration of the masticator muscle and temporomandibular joints (TMJs). TMJ inflammation is considered to be a cause of pain in patients with TMD. Extracellular proteolytic enzymes, specifically the matrix metalloproteinases (MMPs), have been shown to modulate inflammation and pain. The purpose of this investigation was to determine whether the expression and level of gelatinolytic activity of MMP-2 and MMP-9 in the trigeminal ganglion are altered during different stages of temporomandibular inflammation, as determined by gelatin... Tipo: Info:eu-repo/semantics/article Palavras-chave: Persistent temporomandibular inflammation; Matrix metalloproteinases; Trigeminal ganglion. Ano: 2013 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2013001100956 Registros recuperados: 5 Primeira ... 1 ... Última

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